【K201】に関連する文献を紹介しています。

• K201 improves aspects of the contractile performance of human failing myocardium via reduction in Ca2+ leak from the sarcoplasmic reticulum.

  Toischer K, Lehnart S E, Tenderich G, Kaneko N et al

  Basic Res Cardiol.2009 Aug:30,2009

• Pharmacological characteristics and clinical applications of K201.

  Kaneko N, Matsuda R, Hata Y, Shimamoto K.

  Current clinical pharmacology 2009 May;4(2):126-131.

• New 1,4-benzothiazepine derivative, K201, demonstrates cardioprotective effects against sudden cardiac cell death and intracellular calcium blocking action

  Noboru Kaneko

  Drug Development Research Volume 33, Issue 4, Date: December 1994, Pages: 429-438

• Crystal structure of annexin V with its ligand K-201 as a calcium channel activity inhibitor

  Noboru Kaneko, Hideo Ago, Ryuko Matsuda, Eiji Inagaki, Masashi Miyano

  Journal of Molecular Biology, Volume 274, Issue 1, 21 November 1997, Pages 16-20

• Inhibition of annexin V-dependent Ca2+ movement in large unilamellar vesicles by K201, a new 1,4-benzothiazepine derivative

  Noboru Kaneko, Ryuko Matsuda, Masashi Toda, Ken Shimamoto

  Biochimica et Biophysica Acta (BBA) - Biomembranes, Volume 1330, Issue 1, 13 November 1997, Pages 1-7

• K201, a multi-channel blocker, inhibits clofilium-induced torsades de pointes and attenuates an increase in repolarization

  Hisashi Hasumi, Ryuko Matsuda, Ken Shimamoto, Yoshihito Hata, Noboru Kaneko

  European Journal of Pharmacology, Volume 555, Issue 1, 19 January 2007, Pages 54-60.

• Norepinephrine-induced diastolic dysfunction with aortic valve opening under calcium-loading in rats

  Noboru Kaneko, Ry uko Matsuda, Takahide Nakajima, Makoto Shinozaki, Naoyuki Ohtani, Kazuhiko Oda, Hisashi Hasumi, Ken Shimamoto

  Drug Development Research Volume 67, Issue 6, Date: June 2006, Pages: 511-518

• K201 Improves norepinephrine-induced diastolic dysfunction with preserved ejection fraction

  Noboru Kaneko, Ryuko Matsuda, Naoyuki Ohtani, Takahide Nakajima, Takuo Arikawa, Hidehiko Suzuki, Shigeru Toyoda, Migaku Kikuchi, Yoshihito Hata, Shichiro Abe, Isao Taguchi, Ken Shimamoto

  Drug Development Research Volume 67, Issue 11, Date: November 2006, Pages: 852-861

• Effects of Novel 1,4-Benzothiazepine Derivative, K201, on Cytosolic Ca2+ and Contraction in Isolated Smooth Muscle of Rat Aorta

  Shimamoto Ken, Kaneko Noboru

  Tokyo Joshi Ikadaigaku Zasshi 74(1) 39-46,2004

• Protective effect of JTV519 on prolonged myocardial preservation

  M. Hachida, H. Lu, N. Kaneko, M. Nonoyama, H. Koyanagi

  Transplantation Proceedings, Volume 31, Issues 1-2, 3 February 1999, Page 1094

• Significant effect of 1,4-benzothiazepine derivative (K2) in improving myocardial preservation

  M. Hachida, N. Kaneko, A. Ohkado, H. Hoshi, M. Nonoyama, S. Saitou, Y. Bonkohara, N. Hanayama, M. Miyagishima, H. Koyanagi

  Transplantation Proceedings Volume 29, Issues 1-2, February-March 1997, Pages 1346-1348

• Defective domain-domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2+ leak in failing hearts

  H Tateishi, M Yano, M Mochizuki, T Suetomi, M Ono, X Xu, H Uchinoumi, S Okuda, T Oda, S Kobayashi, T Yamamoto, Y Ikeda, T Ohkusa, N Ikemoto, M Matsuzaki

  Cardiovasc Res. 2008 Dec 2.,2008

• Identification of Target Domains of the Cardiac Ryanodine Receptor to Correct Channel Disorder in Failing Hearts

  Takeshi Yamamoto, Masafumi Yano, XiaoJuan Xu, Hitoshi Uchinoumi, Hiroki Tateishi, Mamoru Mochizuki, Tetsuro Oda, Shigeki Kobayashi, Noriaki Ikemoto, and Masunori Matsuzaki

  Circulation 117: 762 - 772, 2008