【K201】に関連する文献を紹介しています。

• Abnormal ryanodine receptor function in heart failure

  Masafumi Yano, Takeshi Yamamoto, Noriaki Ikemoto, Masunori Matsuzaki

  Pharmacology & Therapeutics, Volume 107, Issue 3, September 2005, Pages 377-391

• Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure

  Xander H. T. Wehrens, Stephan E. Lehnart, Steven Reiken, Roel van der Nagel, Raymond Morales, Jie Sun, Zhenzhuang Cheng, Shi-Xiang Deng, Leon J. de Windt, Donald W. Landry, and Andrew R. Marks

  PNAS 2005 102:9607-9612; published online before print June 22, 2005

• Phosphodiesterase 4D Deficiency in the Ryanodine-Receptor Complex Promotes Heart Failure and Arrhythmias

  Stephan E. Lehnart, Xander H.T. Wehrens, Steven Reiken, Sunita Warrier, Andriy E. Belevych, Robert D. Harvey, Wito Richter, S.-L. Catherine Jin, Marco Conti, Andrew R. Marks

  Cell, Volume 123, Issue 1, 7 October 2005, Pages 25-35

• Correction of Defective Interdomain Interaction Within Ryanodine Receptor by Antioxidant Is a New Therapeutic Strategy Against Heart Failure

  Masafumi Yano, Shinichi Okuda, Tetsuro Oda, Takahiro Tokuhisa, Hiroki Tateishi, Mamoru Mochizuki, Toshiyuki Noma, Masahiro Doi, Shigeki Kobayashi, Takeshi Yamamoto, Yasuhiro Ikeda, Tomoko Ohkusa, Noriaki Ikemoto, and Masunori Matsuzaki

  Circulation, Dec 2005; 112: 3633 - 3643.

• Defective Ryanodine Receptor Interdomain Interactions May Contribute to Intracellular Ca2+ Leak: A Novel Therapeutic Target in Heart Failure

  Stephan E. Lehnart, Xander H.T. Wehrens, and Andrew R. Marks

  Circulation, Jun 2005; 111: 3342 - 3346.

• Defective Regulation of Interdomain Interactions Within the Ryanodine Receptor Plays a Key Role in the Pathogenesis of Heart Failure

  Tetsuro Oda, Masafumi Yano, Takeshi Yamamoto, Takahiro Tokuhisa, Shinichi Okuda, Masahiro Doi, Tomoko Ohkusa, Yasuhiro Ikeda, Shigeki Kobayashi, Noriaki Ikemoto, and Masunori Matsuzaki

  Circulation, Jun 2005; 111: 3400 - 3410.

• Defective Cardiac Ryanodine Receptor Regulation During Atrial Fibrillation

  John A. Vest, Xander H.T. Wehrens, Steven R. Reiken, Stephan E. Lehnart, Dobromir Dobrev, Parag Chandra, Peter Danilo, Ursula Ravens, Michael R. Rosen, and Andrew R. Marks

  Circulation, Apr 2005; 111: 2025 - 2032.

• Protection from Cardiac Arrhythmia Through Ryanodine Receptor-Stabilizing Protein Calstabin2

  Xander H. T. Wehrens, Stephan E. Lehnart, Steven R. Reiken, Shi-Xian Deng, John A. Vest, Daniel Cervantes, James Coromilas, Donald W. Landry, and Andrew R. Marks

  Science 9 April 2004 304: 292-296

• Sudden Death in Familial Polymorphic Ventricular Tachycardia Associated With Calcium Release Channel (Ryanodine Receptor) Leak

  Stephan E. Lehnart, Xander H.T. Wehrens, Paivi J. Laitinen, Steven R. Reiken, Shi-Xiang Deng, Zhenzhuang Cheng, Donald W. Landry, Kimmo Kontula, Heikki Swan, and Andrew R. Marks

  Circulation, Jun 2004; 109: 3208 - 3214.

• Annexin V disruption impairs mechanically induced calcium signaling in osteoblastic cells

  T. L. Haut Donahue, D. C. Genetos, C. R. Jacobs, H. J. Donahue, C. E. Yellowley

  Bone, Volume 35, Issue 3, September 2004, Pages 656-663

• 2APB- and JTV519(K201)-sensitive micro Ca2+ waves in arrhythmogenic Purkinje cells that survive in infarcted canine heart

  Penelope A. Boyden, Wen Dun, Chirag Barbhaiya, Henk E. D. J. ter Keurs

  Heart Rhythm, Volume 1, Issue 2, July 2004, Pages 218-226

• Sparking the failing heart.

  Farr Maryjane A, Basson Craig T

  N Engl J Med 351:185-187,2004

• Novel therapeutic approaches for heart failure by normalizing calcium cycling.

  Wehrens Xander H T, Marks Andrew R

  Nat Rev Drug Discov 3:565-573,2004