Pipeline関連文献
【K201】に関連する文献を紹介しています。
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Annexin-mediated Ca2+ Influx Regulates Growth Plate Chondrocyte Maturation and Apoptosis
Wei Wang, Jinping Xu, and Thorsten Kirsch
J. Biol. Chem., Jan 2003; 278: 3762 - 3769
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Antiarrhythmic effects of JTV-519, a novel cardioprotective drug, on atrial fibrillation/flutter in a canine sterile pericarditis model.
Kumagai K
J Cardiovasc Electrophysiol 14(8): 880- 884, 2003
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A new cardioprotective agent, JTV519, improves defective channel gating of ryanodine receptor in heart failure
Masateru Kohno, Masafumi Yano, Shigeki Kobayashi, Masahiro Doi, Tetsuro Oda, Takahiro Tokuhisa, Shinichi Okuda, Tomoko Ohkusa, Michihiro Kohno, and Masunori Matsuzaki
Am J Physiol Heart Circ Physiol, Mar 2003; 284: H1035 - H1042.
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Treatment of Heart Failure Through Stabilization of the Cardiac Ryanodine Receptor
Gerd Hasenfuss and Tim Seidler
Circulation, Jan 2003; 107: 378 - 380.
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FKBP12.6-Mediated Stabilization of Calcium-Release Channel (Ryanodine Receptor) as a Novel Therapeutic Strategy Against Heart Failure
Masafumi Yano, Shigeki Kobayashi, Masateru Kohno, Masahiro Doi, Takahiro Tokuhisa, Shinichi Okuda, Masae Suetsugu, Takayuki Hisaoka, Masakazu Obayashi, Tomoko Ohkusa, Michihiro Kohno, and Masunori Matsuzaki
Circulation, Jan 2003; 107: 477 - 484.
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Sealing the leak,healing the heart.
Most Patrick, Koch Walter J
Nat Med 9:993-994,2005
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Role of protein kinase C isozymes in cellular functions and pathological conditions
Hisayama T
Nippon Yakurigaku Zasshi 119(2):65- 78, 2002
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Retinoic acid stimulates annexin-mediated growth plate chondrocyte mineralization
Wei Wang and Thorsten Kirsch
J. Cell Biol., Jun 2002; 157: 1061- 1070.
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A Novel Cardioprotective Agent, JTV-519, Is Abolished by Nitric Oxide Synthase Inhibitor on Myocardial Metabolism in Ischemia-Reperfused Rabbit Hearts
Hitoshi KAWABATA, Kizuku NAKAGAWA and Kinji ISHIKAWA
Hypertens Res 25(2):303-309, 2002
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Reversal of P-glycoprotein mediated multidrug resistance by a newly synthesized 1,4-benzothiazipine derivative, JTV-519
Xiao-Fang Che, Yuichi Nakajima, Tomoyuki Sumizawa, Ryuji Ikeda, Xiao-Qin Ren, Chun-Lei Zheng, Motoi Mukai, Tatsuhiko Furukawa, Misako Haraguchi, Hui Gao, Yoshikazu Sugimoto, Shin-ichi Akiyama
Cancer Letters, Volume 187, Issues 1-2, 10 December 2002, Pages 111-119
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Reversal of cisplatin resistance by the 1,4-benzothiazepine derivative, JTV-519.
Nakamura T, Koizumi F, Kaneko N, Tamura T, Chiwaki F,Koh Y,Akutagawa S,Saijo N,Nishio K
Jpn J Cancer Res 92(6): 597- 602, 2001
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Inhibitory effects of JTV-519, a novel cardioprotective drug, on potassium currents and experimental atrial fibrillation in guinea-pig hearts
Haruaki Nakaya, Yoshie Furusawa, Takehiko Ogura, Masaji Tamagawa, and Hiroko Uemura
Br J Pharmacol. 2000 December; 131(7): 1363-1372.